1. Letrozole raw Description:
Product name: Letrozole raw
CAS No.: 112809-51-5
M.F.: C17H11N5
M.W.: 285.3
Assays: 99%
Packing: 5kg/tin
Reference Standard: USP30
Appearance: White or Almost White Crystalline Powder
Refrigeration save: Room temperature more than 20 Celsius degree to agglomerate,or so 30 Celsius degree into a liquid.
2. Letrozole raw Specification：
Femara is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women.
Femara is intended for use only by women who are no longer of childbearing age. Possible candidates must have already ceased to menstruate.
It is often used in patients who have already undergone other cancer treatments, such as radiation, chemotherapy, and used other cancer drugs, like tamoxifen. This nonsteroidal aromatase inhibitor may help prevent any remaining cancer cells from spreading.
Femara is used for the treatment of post-menopause breast cancer.
Femara is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia.
It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system.
3. Letrozole raw Application:
| Tests | Specifications | Results |
| Appearance | White or off-white crystaline powder | White Crystalline powder |
| Solubility | Soluble in Chloroform; Soluble in ethanol when heated |
Conform |
| ldentification | (1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm |
Conform Conform |
| (2)Infrared spectrum should be in accordance
the dominant peak of contrast |
In accordance with the
dominant peak of contrast |
|
| Melting points | 182ºC-184ºC | 182ºC |
| Related substances | ≤0.5% | 0.3% |
| Single impurity | ≤0.3% | 0.2% |
| Loss on drying | ≤1.0% | 0.8% |
| [Assay]C17H11N5 (On anhydrous basis) |
≥98.0% | 99.2% |
| Conclusion | Conforms Specifications of Enterprise Standard. | |
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Femara, sold under the brand name Femara, is a prescription drug used to treat breast cancer in its advanced stages, and in women who have finished menopause.
Doctors may use Femara off-label in fertility treatments to help encourage egg release (ovulation) in women.
Femara belongs to a class of cancer drugs known as aromatase inhibitors, which work by preventing the body from converting a hormone called androgen into estrogen.
This treatment has proven beneficial in cancers whose growth seems to be encouraged by excess estrogen in the body, like certain types of breast cancer.
Originally manufactured by Novartis, the Food and Drug Administration (FDA) first approved Femara in 1997.
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Commerce Clause
| Minimum Order Quantity: | Negotiation |
| Price: | Negotiation |
| Payment Terms: | Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin |
| Delivery time: | Within 24 hours after receiving the payment |
| Leading time: | 4~6 working days after confirming the payment |
| Delivery | By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door) |
| Packaging Details: | Discreet and Disguised packing |
| Supply Ability: | Mass in stock |
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