Weigh Loss Steroids Powder Breast Carcinoma Cancer Treatment Arimidex Anastrozoles CAS 120511-73-1
1. Arimidex / anastrozole raw Description:
Product name: Arimidex / anastrozole raw
CAS No.: 120511-73-1
M.F.: C17H19N5
M.W.: 293.37
Assays: 99%
Packing: 5kg/tin
Reference Standard: USP30
Appearance: White or Almost White Crystalline Powder
Refrigeration save: Room temperature more than 20 Celsius degree to agglomerate,or so 30 Celsius degree into a liquid.
2. Arimidex / anastrozole raw Specification:
Anastrozoles Arimidex is the aromatase inhibitor of choice. Arimidex’s mechanism of action – blocking conversion of aromatizable steroids to estrogen – is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid) or (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others.
Anastrozoles is an aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and postmenopausal women. The severity of breast cancer is increased by estrogen, as sexhormones cause hyperplasia, and differentiation at estrogen receptor sites. Anastrozoles works by inhibiting the synthesis of estrogen.
The trial suggested that anastrozoles is the preferred medical therapy for Postmenopausal women with localized breast cancer that is estrogen receptor (ER) positive.
3. Arimidex / anastrozole raw Application:
Items | Standard | Results |
Description | White crystalline powder | Complies |
Identification | IR HPLC Reactive | Conform with standard IR Conform with standard HPLC Conform |
Solubility | Freely soluble in methanol,acetone, ethanol and tetrahydrofuran. And very soluble in acetonitrile | Complies |
Total Impurity | max.0.5% | 0.18% |
Total Unspecified Impurity | max. 0.2% | 0.08% |
Individual unspecified impurlty | max. 0.1% | 0.05% |
Related compound B | max. 0.2% | 0.07% |
Related compound C | max. 0.2% | 0.04% |
Related compound D | max. 0.1% | 0.05% |
Related compound E | max. 0.1% | 0.06% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0ºC | 82.5~83.2ºC |
Water | max. 0.3% | 0.21% |
Residue on ignition | max. 0.1% | 0.07% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%~102.0% | 99.8% |
Storage | Cool and dry |
Conclusion | It complies to USP32 . |
Anastrozol is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren.
It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
Usage:
(1) It is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients.
(2) Its used to cure the breast cancer.
(3) Arimidex is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients. It is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. Its used to cure the breast cancer, particularly suitable for postmenopausal women with advanced breast cancer who recrudescent after hormone adjuvant therapy.
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Commerce Clause
Minimum Order Quantity: | Negotiation |
Price: | Negotiation |
Payment Terms: | Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin |
Delivery time: | Within 24 hours after receiving the payment |
Leading time: | 4~6 working days after confirming the payment |
Delivery | By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door) |
Packaging Details: | Discreet and Disguised packing |
Supply Ability: | Mass in stock |